Preliminary Investigation of Antipyretic Activity of Trinpanchmool Extracts

Soma Jayalakshmi, Ashoke K Ghosh, Birendra Shrivastava, RAJEEV KUMAR SINGLA


Current research work is to evaluate the antipyretic activity of hydro-alcoholic extract of trinpanchmool on the wistar rats. Brewer’s yeast induced pyrexia method was used to evaluate febrifuge effect of trinpanchmool extract along with its comparison with its individual constituents on the wistar rats. Darbh, Ikshu and SAR was having better antipyretic activity than the standard drug paracetamol. Combination of the drugs was having better antipyretic that paracetamol but lesser than the individual drugs. Trinpanchmool and its individual drugs are having febrifugatic effect better than our standard paracetamol.

Full Text:



K Ashok Kumar et al. Chemical Composition & antimicrobial activity of the essential oil of Desmostachya bipinnata linn. International Journal of Phytomedicine. 2010; 2: 436-439.

Medha M Hegde et al. Assessment of antidiarrhoeal activity of desmostachya bipinnata linn.(Poaceae) root extracts. Boletin Latinoamericano Y Del caribe De Plantas medicinales Y Aromaticas. 2010; 9(4): 312-318.

Mohammad A Ramadan & N A Safwat. Antihelicobacter activity of a flavanoid compound isolated from Desmostachya bipinnata. Australian Journal of Basic & Applied Sciences. 2009; 3(3): 2270-2277.

Sabina Shrestha et al. A New xanthene from Desmostachya bipinnata (L.) stapf inhibits signal transducer and activator of transcription 3(STAT3) and low density lipoprotein oxidation. J Korean Soc. Appl. Biol. Chem. 2011; 54(2): 308-311.

Md. Mynol IslamVhuiyan et al. Antidiarrhoeal & CNS depressant activity of methanolic extract of Saccharum spontanuem Linn. Stamford Journal of Pharmaceutical Sciences. 2008; 1(1&2): 63-68.

Ghani A. Medicinal plants of Bangladesh with chemical constituents and uses, 2nd edn pp

The Asiatic society of Bangladesh, Dhaka, 2003.

Nikodemus TW, Padmawinata K, Soetarno S. Phenolic acids from imperata cylindrical (L) Raeusch. Var. Major (Nees) c.e. hubb. Medicaments et ailments: L` approche ethnopharmacologique. 337.

EE Mak-mensah, G Komlaga, E O Terlabi. Antihypertensive action of ethanolic extract of Imperata cylindrical leaves in animal models. Journal of Medicinal Plants Research. 2010; 4(14): 1486-1491.

Dae-young Lee et al. A new lignin glycoside from the rhizomes of imperata cylindrica. Journal of asian natural product research. 2008; 10(4): 299-302.

Rahar Sandeer et al. Medicinal Aspects of Saccharum munja. Research journal of Pharmacy & Technology. 2010;3(3):636-639.

Joaquim M Duarte-Almeida et al. Antioxidant activity of phenolic compounds from sugar cane (Saccharum officinarum L) Juice. Plant foods for Human Nutrition. 2006; 61: 187-192.

Jain BB et al. Antipyretic activity of aqueous extract of leaves of cocculus hirsutus. Indian Journal of Natural Product. 2000; 23:26-29.

Metowogo K et al. Antiulcer and Antiinflammatory Effects of Hydroalcohol Extracts of Aloe buettneri A. Berger Liliaceae). Tropical journal of pharmaceutical research. 2008; 7: 907-912.


  • There are currently no refbacks.

Copyright (c)

                AR Journals

Street 1st, Gaytri Vihar, Pinto Park, Gwalior, M.P. India

     (Design) 2009-2021


Follow @arjournals on Twitter