Phytochemical Screening and Analgesic Activity of Opuntia ficus indica cladods extract in Wistar rats

Sihem HALMI, Madi A, Zeguad N, Berouel K, Lemoui R, Benlakssira B, Hamdi pacha Y


   The purpose of this work is the study of the peripheral and central analgesic activity of the Opuntia ficus indica cladods extract. Different concentrations are tested: 1000 mg/kg; 2000 mg/kg and 3000 mg/kg of body weight on rats by three different methods: the tail flick, the hot-plate and the writhing test to the acetic acid. The results obtained show that the aqueous extract of the cladods has an peripheral and central analgesic activity comparable to that of the Aspirin after administration to rats. The phytochemical analysis of the extract reveals the presence of tannins, coumarins, flavonoids, steroids and anthocyanins whose properties can be used to advantage in the treatment of pain. Our results confirm the traditional use of  Opuntia ficus-indica cladods as an analgesic.


Extract; Phytochemical; Pain; Analgesic; Opuntia ficus indica

Full Text:



  • There are currently no refbacks.

Copyright (c) 2016 Sihem HALMI

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

                AR Journals

Street 1st, Gaytri Vihar, Pinto Park, Gwalior, M.P. India

     (Design) 2009-2021


Follow @arjournals on Twitter