Eradicating Potential of Achyranthes aspera

Vivek Dave, Swapnil Sharma, Km. Ruby, Sachdev Yadav, Jitendra Bajaj

Abstract


The antioxidant activity of Achyranthes aspera methanolic aerial part extracts was investigated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging and ferric-reducing antioxidant power assays. Quantitative estimation of total flavonoid and phenolic content was performed followed by thin layer chromatography (TLC) to confirm the presence of secondary metabolites in the extract.

From results of DPPH and ferric-reducing antioxidant power assays, it was found that methanolic aerial part extracts of Achyranthes aspera precipitates strong antioxidant (P < 0.005) activity compared to the ascorbic acid. The concentrations of total flavonoid and total phenolic content were found to be 47.6 mg RuE/g and 28.66 mg GAE/g respectively. The TLC study showed distinguished spots and revealed the presence secondary metabolites.


Keywords


Achyranthes aspera, methenolic extract, antioxidant activity, quantitative analysis

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References


Badami S, Gupta M.K, and Suresh B, Antioxidant activity of ethanolic extract of Striga orobanchioides. J. Ethnopharmacol. 2003; 85: 227-230.

Hazra B, Santana B, Nripendranath M. Antioxidant and free radicals scavenging activity of Spondias pinnata. J. BMC. 2008; 8: 63.

Jose A. Yuri. Antioxidant activity and total phenolics concentration in apple peel and flesh is determined by cultivar and agroclimatic growing regions in Chile Journal of Food, Agriculture & Environment 2009; 7 : 513-517.

Valko M, Leibfritz D, Moncola J, Mazura M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. International Journal Biochemistry Cell Biology, 2007; 39, 44–84.

Huda-Faujan, N, Noriham, A, Norrakiah A. S, Babji A. S. Antioxidant activity of plants methanolic extracts containing phenolic compounds. African Journal of Biotechnology. 2009; Vol. 8 (3): pp. 484-489

Sumazian Y, Syahida A, Hakiman M, Maziah M, Antioxidant activities, flavonoids, ascorbic acid and phenolic contents of Malaysian vegetables. J. Med. Plant. Res. 2010; 4(10): 881-890.

T Sun; Ho CT. Antioxidant and Antibacterial Activities of Various Extracts and Fractions of Fresh Tea Leaves and Green Tea . Food Chemistry, 2005; 90: 743-749.

Suhaj M. Spice antioxidants isolation and their antiradical activity: a review. Journal of Food Composition and Analysis, 2006; 19: 531-537.

Hirose M, Imaida K, Tamano S, Ito, N. Cancer chemoprevention by antioxidants. In “Food Phytochemicals for Cancer Prevention II”. 1994; 122-132.

Girach RD, Khan ASA. Ethnomedicinal uses of Achyranthes aspera leaves in Orissa (India). Int J Pharmacogn.1992; 30:113-115.

Liersch Bkher. Achyranthes. In: Haensel R, Keller K, Rimpler G, Schneider G (eds) Hagers Handbuch der Pharmazeutischen Praxis. V. Springer-Verlag. Berlin7, 1992; 54-59.

Jain SK. Dictionary of Indian folk medicine and ethnobotany. Deep Publications, New Delhi, India.1991.

Bhom KH, Liersch R, Haensel R, Keller K, Rimpler H. Schneider (Eds.).G, Hagers Handbchder Pharmazeutischen Praxis Springer Verlag. Berlin. 1992;5,54-59.

Vasudeva N, Sharma SK. Estrogenic and pregnancy interceptory effects of Achyranthes aspera Linn. Root. J.Ethanopharmacol. 2006;179.

Paul D, Bera S, Jana D, Maiti R. Ghosh.D. In Vitro determination of the contraceptive spermicidal activity of a composite extract of Achyranthes aspera and Stephania hernandifolia on human semen. Contraception. 2006; 73:284-288.

Mohammad SA Javed I. evaluation of hypoglycemic effect of Achyranthus aspera in normal and alloxan diabetic rabbit. Journal of Ethanopharmacology 1991; 31(1):49-57.

Chang C, Yang M, Wen H, Chern J. Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J. Food Drug Anal. 2002; 10: 178-182

McDonald S, Prenzler PD, Antolovich M, Robards K Phenoliccontent and antioxidant activity of olive extracts. Food Chem. 2001; 73:73-84.

Koleva II, Van Beek TA, Linssen JPH, Screening of plant extracts for antioxidant activity: a comparative study on three testing methods. Phytochem. Anal. 2002; 13: 8-12.

Athukorala Y, Kim KN, Jeon YJ. Antiproliferative and antioxidant properties of an enzymatic hydrolysate frombrown alga Ecklonia cava. Food Chem. Toxicol. 2006; 44: 1065-1074.

Yen, G. C., & Duh, P. D. Antioxidative properties of methanolic extracts from peanut hulls. Journal of the American Oil Chemists Society. 1993; 70, 383–386

Wagner H, Bladt S, zgainski E M. Plant drug analysis. A thin layer chromatography atlas, springer. germany, 2nd edn, 1984.

Shahidi F, Wanasundara PKJPD. Phenolic antioxidants. Critical Reviews in Food Science and Nutrition Critical Reviews in Food Science and Nutrition. 1992; 32: 67-103.

Halliwell B Free radicals, antioxidants and human disease: curiosity, cause, or consequence Lancet 1994; 344: 721-724.


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