Antimicrobial activity of Saraca indica against clinical pathogens

Hema TA, Parvathy J, Shiny M

Abstract


The antimicrobial activity of flowers of the medicinal plant Saraca indica collected from from the regions of Ambalathara, Kerala, South India was checked against the clinical pathogens by well diffusion method. Saraca indica showed highest antimicrobial activity on methanolic extracts. The phytochemical evaluation showed the presence of alkaloids, tannins, proteins and reducing sugars. With the help of column chromatography the methanolic extract was purified and highest antimicrobial activity was observed in the concentration 2:8. By thin layer chromatography the compounds are separated and the Rf value obtained was 0.6. The compound responsible for the antimicrobial activity was identified as alkaloids.

Keywords


Saraca indica, antimicrobial activity, alkaloids, Rf value.

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References


Gopinath.S.M

Department of Biotechnology,

Acharya Institute of Technology,

Bangalore- 90

Email:gopinath@acharya.ac

Bhadauria Preethi

Department of Pharamaceutical Chemistry

Agra public pharmacy college

Agra (UP)

India

Email vmat1987@gmail.com

Dr. A. Lakshmana Rao

V. V. Institute of Pharmaceutical Sciences, Gudlavalleru- 521 356,

A.P., India.

E-mail: dralrao@gmail.com


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