Status of research results in chemistry of biologically active substances in Benin

Alain Y Koudoro, Christian Tetede Rodrigue Konfo, Philippe Sessou, Dominique C K Sohounhloue

DOI: http://dx.doi.org/10.5138/09750185.2251

Abstract


Research on biologically active chemicals extracted from medicinal plants and essential oils from aromatic plants in the West African subregion is booming. Recognition of the clinical, pharmaceutical and economic value of herbal medicines continues to grow despite the growth of the pharmaceutical industry and the continued development of new, more effective synthetic and biological medical products. On the other hand, despite the improvement in food preservation technics, food preservatives nature remains one of the most important issues for public health. Indeed, several synthetic preservatives have been banned in some countries because of their long-term adverse toxicological effects. The current trend of consumers to seek for a more natural diet has prompted the research, development and application of new natural products with antimicrobial and antioxidant activities in order to use them as alternatives to synthetic preservatives. This review aims to do an inventory of the results of research in chemistry of biologically active substances in Benin.

Keywords


Biologically active substances; food preservation; human and veterinary; pharmacopoeias; plant extracts; public health.

Full Text:

PDF

References


  1. Jiofack T, Fokunang C, Guedje N, Kemeuze V, Fongnzossie E, Nkongmeneck B A, Tsabang N. Ethnobotanical uses of medicinal plants of two ethnoecological regions of Cameroon. Int. J. Med. Med. Sci. 2010; 2(3): 60-79.
  2. Laplante J. Le médicament aux frontières des savoirs humanitaires et autochtones. Anthropologie et sociétés, 2003; 27(2): 59-75.
  3. Salhi S, Fadli M, Zidane L, Douira A. Etudes floristique et ethnobotanique des plantes médicinales de la ville de Kénitra (Maroc). Lazaroa, 2010 ; 31 : 133.
  4. Lawin IF, Laleye OAF, Agbani O P. Vulnérabilité et stratégies endogènes de conservation des plantes utilisées dans le traitement du diabète dans les communes de Glazoué et Savè au Centre-Bénin. Int. J. Biol. Chem. Sci., 2016 ; 10(3) : 1069-1085.
  5. Codjia JTC, Assogbadjo AE, Ekué MRM. Diversité et valorisation au niveau local des ressources végétales forestières alimentaires du Bénin. Cahiers agricultures, 2003 ; 12(5) : 321-331.
  6. Adomou AC, Yedomonhan H, Djossa B, Legba SI, Oumorou M, Akoegninou, A. Etude Ethnobotanique des plantes médicinales vendues dans le marché d’Abomey-Calavi au Bénin. Int. J. Biol. Chem. Sci. 2012; 6(2): 745-772.
  7. Alitonou GA, Avlessi F, Tchobo FP, Noudogbessi JP, Tonouhewa A, Yehouenou B, Menut C, Sohounhloue KD. Chemical composition and biological activities of essential oils from leaves of Cymbopogon giganteus Chiov. and Cymbopogon schoenanthus (L.) spreng (Poaceae) from Benin. Int. J. Biol. Chem. Sci. 2012; 6 (4): 1819-1827.
  8. Koudoro YA, Agbangnan DCP, Yèhouénou B, Tchobo FP, Alitonou GA, Avlessi F, Akoègninou A, Sohounhloué KCD. Chemical characterization and biological activities of extracts from two plants (Cissus quadrangularis and Acacia polyacantha) used in veterinary medicine in Benin. J. Pharmacogn. Phytochem. 2015; 3(6): 91-96.
  9. Medoatinsa SE, Agbangnan CP, Viwami F, Bogninou AGSR, Noudogbessi JP, Lagnika L, Ahissou H, Sohounhloue DCK. In vitro antiplasmodial and antioxidant activities of ethanolic and hydroethanolic extracts of hyptis Suaveolens, World J Pharm Pharm Sci.2015; 4(08):101-112 ;
  10. Konfo CTR, Worou C N., Dahouenon-Ahoussi E, Cakpo-Chichi M, Soumanou MM, Sohounloué DCK. Improvement of African traditional sorghum beers quality and potential applications of plants extracts for their stabilization: a review. J. Microbiol. Biotechnol. Food Sci. 2015 ; 5 (2): 190-196;
  11. Yehouenou B, Ahoussi E, Sessou P, Alitonou GA, Toukourou F, Sohounhloué DCK. Chemical composition and antimicrobial activities of essential oils (EO) extracted from leaves of Lippia rugose A. Chev against foods pathogenic and adulterated microorganisms. Afr. J. Microbiol. Res. 2012; 6 (26): 5496-5505.
  12. Mamadou SR, Moussa I, Sessou P, Yehouenou B, Agbangnan P, Illagouma A, Abdoulaye A, Sohounhloué D, Ikhiri K. Etude phytochimique, activités antiradicalaire, antibactérienne et antifongique d’extraits de Sebastiania chamaelea (L.) Müll.Arg, J. Soc. Ouest Afr. Chim. 2014 ; 037 :10-17.
  13. Chabi NW, Konfo TRC, Adjagba M, Moussedikou L, Ahoussi- Dahouenon E, Layeye A, Gbaguidi C, Soumanou MM. Evaluation of the Toxicity of Hemizygia bracteosa (Benth) Plant Used in Traditional Medicine for the Treatment of Diabetes Mellitus in Benin. Am. J. Biomed. Res. 2015: 3(3): 40-44.
  14. Houndje EB, Ogni CA, NoudekeN, Farougou S, Youssao AKI, Kpodekon TM. Recettes ethno-vétérinaire à base de plantes médicinales utilisées pour le traitement de la fièvre aphteuse au Bénin. Int. J. Biol. Chem. Sci. 2016; 10(5): 2090-2107.
  15. Dassou HG, Ogni CA, Yédomonhan H, Adomou AC, Tossou M, Dougnon J. T, Akoègninou A. Diversité, usages vétérinaires et vulnérabilité des plantes médicinales au Nord-Bénin. Int. J. Biol. Chem. Sci. 2014; 8(1), 189-210.
  16. Ogni C A, Kpodékon MT, Dassou HG, Boko CK, Koutinhouin BG, Dougnon JT,Akoegninou A. Inventaire ethno-pharmacologique des plantes utilisées dans le traitement des pathologies parasitaires dans les élevages extensifs et semi-intensifs du Bénin. Int. J. Biol. Chem. Sci. 2014; 8(3): 1089-1102.
  17. Koudoro YA, Dedome OLO, Yehouenou B, Yovo M, Agbangnan DCP, Tchobo FP, Alitonou GA, Akoegninou A,Sohounhloue KD. Free radical scavenging and antibacterial potential of two plants extracts (Khaya senegalensis and Pseudocedrela kotschyi) used in veterinary pharmacopoeia in Benin. Elixir Appl. Chem, 2014; 76: 28720-28726.
  18. Fandohan P, Zoumenou D, Hounhouigan D J, Marasas W FO, Wingfield MJ, Hell K. Fate of aflatoxins and fumonisins during the processing of maize into food products in Benin. Int. J. Food Microbiol. 2005; 98(3): 249-259.
  19. Kpatinvoh B, Adjou ES, Dahouenon-Ahoussi E, Konfo C, Atrevy B, Sohounhloue DCK. Problématique de la conservation du niébé (Vigna unguiculata L.) en Afrique de l‟Ouest : étude d’impact et approche de solution. J. Anim. Plant Sci. 2016 ; 31(1) : 4831-4842.
  20. Bossou DA, Ahoussi E, Ruysbergh E, Adams A, De Kimpe N, Avlessi F, Sohounhloue CKD, Mangelinckx S, Smagghe G. Characterization of volatile compounds from three Cymbopogon Species and Eucalyptus citriodora from Benin and their insecticidal activities against Tribolium castaneum,. Ind. Crops Prod. 2015; 76: 306–317.
  21. Adjalian E, Sessou P, Bothon TDF, Dangou J, Odjo T, Figueredo G, Noudogbessi JP, Kossou D, Menut C, Sohounhloue D. Chemical composition and bioefficacy of Dennettia tripetala and Uvariodendron angustifolium leaves essential oils against the angoumois grain moth, Sitotroga cerealella. Int. J. Biosci. 2014; 5(8): 161-172;
  22. Adjalian E, Sessou P, Yehouenou B, Bothon TDF, Noudogbessi JP, Dansou K, Menut C, Sohounhloue D. Anti-oviposition and repellent activity of essential oil from melaleuca leucadendron leaf acclimated in bénin against the angoumois grain moth. Int. J. Biol. Pharm. Allied Sci. 2015; 4(2): 797-806;
  23. Adjalian E, Sessou P, Alitonou GA, Noudogbessi JP, Kossou D, Menut C, Sohounhloue D. Ovicide and Larvicide Activities of the Essential Oils Extracted from Polyalthia longifolia and Clausena anisata on Sitotroga cerealella. Online J. Biol. Sci. 2017; 17(3):193-200.
  24. Koudoro YA, Yovo M, Yehouenou B, Agbangnan DCP, Tchobo FP, Alitonou GA, Sohounhloue CKD. Chemical study, antiradical and antibacterial potential of the extracts of Ximenia americana and Cussonia arborea of Benin. World J Pharm Sci. 2014; 2(12): 1626-1635.
  25. Koudoro YA, Dedome O, Yehouenou B, Yovo M, Agbangnan DCP, Tchobo FP, Sohounhloue KCD. Free radical scavenging and antibacterial potential of two plants extracts (Khaya senegalensis and Pseudocedrela kotschyi) used in veterinary pharmacopoeia in Benin. Elixir Int. J. 2014; 76: 28720-28726.
  26. Koudoro YA, Wotto DV, Konfo TRC, Agbangnan DCP, Sohounhloue CKD. Phytochemical screening, antibacterial and anti-radical activities of Daniellia oliveri trunk bark extracts used in veterinary medicine against gastrointestinal diseases in Benin, Int. J. Adv. Res. 2015; 10 (3): 1190-1198.
  27. Bossou AD, Mangelinckx S, Yedomonhan H, Boko PM, Akogbeto MC, De Kimpe N, Sohounhloue DC. Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles). Parasites & vectors, 2013; 6(1): 337.
  28. Koudoro YA, Dedomè LSO, Yovo M, Agbangnan DCP, Tchobo FP, Alitonou GA, Avlessi F, Sohounhloué CKD. Caractérisation chimique, activités antiradicalaire et antibactérienne des extraits de l’écorce de racine de Cochlospermum planchoni du Bénin. IJIAS. 2014 ; 4 (7) : 1582-1594.
  29. Koudoro YA, Dossa CPA, Yèhouénou BB, Tchobo FP, Alitonou GA, Avlessi F, Sohounhloué DC. Phytochemistry, antimicrobial and antiradical activities evaluation of essential oils, ethanolic and hydroethanolic extracts of the leaves of Eucalyptus citriodora hook from Benin. Scientific Study & Res. 2014; 15(1): 59;
  30. Koudoro YA, Alitonou GA, Sossou DJ, Yehouenou B, Avlessi F, Menut C, Sohounhloue, D. Chemical Composition and biological Activities of Essential Oil from Benin Diplolophium africanum Turcz stem leaves. J. Soc Ouest Afr. Chim. 2011; 032: 1-8;
  31. Avlessi F, Alitonou GA, Djenontin TS, Tchobo F, Yèhouénou B, Menut C, Sohounhloué D. Chemical composition and Biological activities of the Essential oil extracted from the Fresh leaves of Chromolaena odorata (L. Robinson) growing in Benin. J. Biol. Sci. 2012; 1(3): 7-13.
  32. Yehouenou B, Wotto V, Bankole H, Sessou P, Noudogbessi JP, Sohounhloue D. Chemical study and antimicrobial activities of volatile extracts from fresh leaves of crassocephalum rubens (juss & jack) s. Moore against food-borne pathogens. Scientific Study & Res. 2010; 11(3): 341-349;
  33. Agbangnan DCP, Tachon C, Bonin C, Chrostowka A, Fouquet E, Sohounhloue DC. Phytochemical study of a tinctorial plant of Benin traditional pharmacopoeia: the red sorghum (Sorghum caudatum) of Benin. Scientific Study & Res. 2012; 13(2): 121-135;
  34. Adjou ES, Kouton S, Dahouenon-Ahoussi E, Soumanou MM, Sohounhloue CKD. Antifungal activityof Ocimum canum Essential oil against Toxinogenic Fungi isolated from Peanut Seeds in post-harvest in Benin. Int. Res. J. Biol. Sci. 2012; 1(7): 20-26;
  35. Bothon FTD, Gnanvossou D, Noudogbessi JP, Hanna R, Sohounhloue D. Bactrocera Cucurbitae response to four Cymbopogon species essential oils. J. Nat. Prod. 2013; (6): 147-155;
  36. Alitonou G, Avlessi F, Sohounhloue CKD, Bessière JM, Menut C. Chemical and biological investigation on volatile constituents of Pentadesma butyracea Sabine (Clusiaceae) from Benin. J Essential Oil Res. 2010; 22: 138-140.
  37. Alitonou GA, Avlessi F, Tchobo FP, Noudogbessi JP, Tonouhewa A, Yehouenou B, Menut C, Sohounhloue KD. Chemical composition and biological activities of essential oils from leaves of Cymbopogon giganteus Chiov and Cymbopogon schoenanthus (L.) spreng (Poaceae) from Benin. Int. J. Chem. Biol Sci. 2012; 6 (4): 1819-1827.
  38. Yehouenou B, Sessou P, Houinsou RL, Noudogbessi JP, Alitonou GA, Toukourou F, Sohounhloué DCK. Chemical composition and Antimicrobial activities of CinnamomumzeylanicumBlume dry Leaves essential oil against Food-borne Pathogens and Adulterated Microorganisms. Int. Res. J. Biol. Sci. 2012; 1(6): 18-25.
  39. Noudogbessi JPA, Tchobo PF, Alitonou GA, Avlessi F, Soumanou M, Chalard P, Figueredo G, Chalchat JC, Sohounhloue DCK. Chemical Study of Extracts of Siphonochilusaethiopicus (Schweinf.) B.L. Burtt (Zingiberaceae) from Benin. Asian J Chem. 2013; 25(15): 8489-8492.
  40. Akibou Osseni ML, Agbangnan DCP, Bossou A, Yedomonhan HP, Avlessi F. Activités antiradicalaires et étude des composés volatils de trois plantes de la médecine traditionnelle du Bénin: Anchomanes difformis, Parkia biglobosa et Polyalthia. IJIAS. 2014 ; 9(4) : 1609-1619.
  41. Bothon FTD, Moutcharaf M, Bogninou GS, Agbangnan CPD, Yehouenou B, Medoatinsa SE, Noudogbessi JP, Avlessi F, Sohounhloue DCK. Chemical Characterization and Biological Activities of Newbouldia laevis and Pterocarpus Santalinoides Leaves. Bull Environ. Pharmacol. Life Sci. 2014; 3 (11): 09-15.
  42. Bossou AD, Mangelinckx S, Yedomonhan H, Boko PM, Akogbeto MC, De Kimpe N, Sohounhloue DC. Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles). Parasites & vectors, 2013; 6(1): 337;
  43. Yovo M, Alitonou GA, Yedomonhan H, Tchobo F, Dedome O, Sessou P, Sohounhloué, D. First report on chemical composition and antimicrobial activity of Artabotrys velutinus Scott-Elliot extracts against some clinical strains in Benin. Am. J. Appl. Chem. 2016; 4: 71-76.
  44. Bothon FTD, Debiton E, Yedomonhan H, Avlessi F, Teulade JC, Sohounhloue DCK. Glucosidase inhibition, antioxidant and cytotoxicity activities of semiethanolic extracts of Bridellia ferruginea benth. and Ceiba pentandra L. Gaerth from Benin. Res. J. Chem. Sci. 2012; 2(12): 31-36.
  45. Keke M, Yèhouénou B, de Souza C, Sohounhloué D. Evaluation of hygienic and nutritional quality of peulh cheese treated by Sorghum vulgaris L and Pimenta racemosa (Miller) extracts. Scientific Study & Research, 2009 ; 10(1) : 29-46.
  46. Houinsou RL, Ahoussi E, Sessou P, Yèhouénou B, Sohounhloué D. Antimicrobial activities of essential oil extracted from leaves of Ocimum gratissimum L. against pathogenic and adulterated microorganisms associated tomato in Benin. International Journal of Biosciences,2012; 2 (11): 90-100.
  47. Degnon GR, Adjou ES, Metome G, Dahouenon-Ahoussi E. Efficacité des huiles essentielles de Cymbopogon citratus et de Mentha piperita dans la stabilisation du lait frais de vache au Sud du Bénin. International Journal of Biological and Chemical Sciences, 2016 ; 10(4) : 1894-1902.
  48. Sessou P, Farougou S, Kaneho S, Djenontin S, Alitonou GA, Azokpota P, Youssao I, Sohounhloue DCK. Bioefficacy of Cymbopogon citratus essential oil against foodborne pathogens in culture medium and in traditional cheese wagashi produced in Benin. International Research Journal of Microbiology. 2012; 3 (12): 406-415.
  49. Adjou ES, Aoumanou MM. Efficacité des extraits de plantes dans la lutte contre les moisissures toxinogènes isolées de l’arachide en post-récolte au Bénin. Journal of Applied Biosciences, 2013 ; 70(1) : 5555-5566.
  50. Dègnon GR, Faton AN, Adjou ES, Noudogbessi JP, Dahouenon- Ahoussi E, Soumanou MM, Sohounhloue DCK. Antifungal potential of Clove essential oil (Syzigium aromaticum L.) in the post-smoking preservation of mackerel (Trachurus trachurus) in Benin. International Research Journal of Biological Sciences, 2013; 2(10): 1-6.
  51. Adjou ES, Dègnon R, Dahouenon-Ahoussi E, Mohamed MS. Chemical composition and biological activity of essential oil from mentha piperita L. leaves on the quality of mango puree during storage. J Microbiol Biotech Food Sci. 2017; 7 (2) 97-100.
  52. Houinssou RF, Adjou ES, Ahoussi ED, Sohounhloué DC, Soumanou MM. Caractéristiques biochimique et sensorielle du niébé (Vigna unguiculata) conservé au moyen des huiles essentielles extraites de plantes de la famille des Myrtaceae [Biochemical and sensorial Characteristics of cowpea (Vigna unguiculata) stored with essential soils extracted from plants of Myrtaceaefamily]. IJIAS. 2014 ; 9(1) : 428.
  53. Kpatinvoh B, Adjou ES, Edwige DA, Konfo TRC, Sohounhloué DC. Problématique de la conservation du niébé (Vigna unguiculata (L), Walp) en Afrique de l’Ouest: étude d’impact et approche de solution. J. Anim. Plant Sci. 2016 ; 31(1) : 4831-4842.
  54. Dahouenon-Ahoussi E; Dègnon GR, Adjou ES, Atodjinou V, Sohounhloue CKD. Amélioration de la technologie de fabrication de la bière à base de matières amylacées locales : utilisation combinée du sorgho (Sorghum bicolor) et de la banane (Musa acuminata). REMISE. 2012 ; 6 (1): 67-83.
  55. Konfo C, Dahouenon-Ahoussi E, Sessou P, Yehouenou B, Djenontin S, De Souza C, Sohounhloué D. Stabilization of local drink "Tchakpalo" produced in Benin by addition of essential oil extracted from fresh leaves of Cymbopogon citratus. Int Res. J. Biol. Sci. 2012; 1(8): 40-49.
  56. Adjou ES, Dahouénon-Ahoussi E, Degnon R, Soumanou MM, Sohounhloue CKD. Bioefficacy of essential oil of Lantana camara from Benin against the growth of fungi and aflatoxin production. JRAA. 2012; 1(4): 112-12.
  57. Adjou ES, Kouton S, Dahouenon-Ahoussi E, Soumanou MM, Sohounhloue CKD. Effect of essential oil from fresh leaves of Ocimum gratissimum L. on mycoflora during Storage of Peanut in Benin, Mycotoxin Res. 2013; 29(1): 29-38.
  58. Adjou ES, Dahouenon-Ahoussi E, Degnon R, Soumanou MM, Sohounhloue CKD. Investigations on bioactivity of essential oil of Ageratum conyzoides L., from Benin against the growth of fungi and aflatoxin production. Int. J. Pharm. Sci. Rev. Res. 2012; 13(1): 143-148.
  59. Dègnon RG, Faton AN, Adjou ES, Tchobo FP, Ahoussi DE, Soumanou MM, Sohounhloue DCK. Efficacité comparée des huiles essentielles de deux plantes aromatiques dans la conservation post-fumage du Chinchard (Trachurus trachurus). J. Anim. Plant Sci. 2013 ; 19(1): 2831-2839.
  60. Zannou A, Konfo TRC, Gbaguidi ANM, Ahoussi-Dahouenon E. Antimicrobial activity of extracts from Cymbopogon citratus L. and of Mentha spicata L. against fungal and bacterial strains isolated from peuhl’s cheese (Waragashi) produced in Benin. Int J. Adv Res. 2015; 3(10): 1684-1695.
  61. Konfo CTR, Chabi NW, Agbadjizo J, Dahouenon-Ahoussi E, Soumanou MM, Sohounhloue DCK. Influence de la feuille de Hemizygia bracteosa(Benth) sur la qualité de la bière du sorgho "tchakpalo" produite au Bénin. IJIAS. 2014 ; 7 (2): 453-463.
  62. Akouedegni CG, Koudande OD, Ahoussi E, Hounzangbe-Adote MS. Effects of Leaves Extract from Spondias Mombin L. and Vitellaria Paradoxa Gaertn F. on West African Dwarf (WAD) Sheep Performance in Republic of Benin. J. Anim. Sci. Adv. 2013; 3(2): 74-82.
  63. Oussalah M, Caillet S, Saucier L, Lacroix M. Inhibitory effects of selected plant essential oils on four pathogen bacteria growth: E. coli O157:H7, Salmonella typhimurium, Staphylococcus aureus and Listeria monocytogenes. Food Control. 2007; 18 (5): 414-420.
  64. Kpoviessi S, Agbani P, Gbaguidi F, Gbénou J, Sinsin BA, Accrombessi G, Quetin-Leclercq J. Seasonal variations of volatile constituents of Hemizygia bracteosa (Benth.) Briq. aerial parts from Benin. Comptes Rendus Chim. 2016; 19(7): 890-894.
  65. Dahouenon-Ahoussi E, Adjou ES, Dègnon G, Konfo RTC, Dahoué R, Soumanou MM, Sohounhloue CKD. Efficiency of the essential oil of Mentha spicata L. in the stabilization of sorghum beer "tchakpalo" produced in Benin. Elixir Int. J. 2017; 104: 46028-46033.
  66. Zannou A, Gbaguidi ANM, Ahoussi-Dahouenon E. Chemical characterization of Tectona grandis, Thalia geniculata, Lasiomorpha senegalensis and of Musa acuminata used as food packing’s in Benin. J. Pharmacogn. Phytochem. 2016; 5(5): 79-82.


Refbacks

  • There are currently no refbacks.
';



Copyright (c) 2018 Dominique Codjo Koko Sohounhloue, Yaya Koudoro, Christian Tetede Rodrigue Konfo, Philippe Sessou

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                AR Journals

18K, Street 1st, Gaytri Vihar, Pinto Park, Gwalior, M.P. India

              Copyright@arjournals.org (Design) 2009-2018

 

Follow @arjournals on Twitter